2025年4月 保髋进展 JCR Q3 区

hip preservation 领域 | 共11篇 | 整理:小马
1
Description of Hip Deformities in 5-Year-Old Patients with Congenital Zika Virus Syndrome: A Cross-Sectional Study.
Revista brasileira de ortopedia Q3 PMID:40297485
Herison Franklin Viana de Oliveira, Francisco Robson Queiroz Rego, Brauner de Souza Cavalcanti, Ítalo Rodrigues Bacellar, Thais Araújo Barbosa
英文摘要 Abstract
无摘要
中文总结
本研究为横断面回顾性研究,纳入62例5岁以上先天性寨卡病毒综合征(CZS)患儿,评估其髋关节畸形特征。结果显示患儿平均月龄65.6±4.1个月,95.2%的患儿GMFCS评分为IV-V级,提示严重运动功能障碍。临床检查示髋关节外展受限(平均41.2±19.5°),Thomas试验平均屈曲畸形16.1±14.9°。影像学方面,Reimers指数平均54.1±34.1%,股骨颈干角158±11.9°,髋臼指数26.0±8.12°。GMFCS V级患儿较III-IV级表现出更高的Reimers指数和髋臼指数。接受内收肌松解手术的患儿外展角度有所改善,但影像学参数无显著变化。该研究提示CZS患儿髋关节脱位发生率高,且功能分级与影像学严重程度相关。长期随访研究仍有必要,以明确此类患儿髋关节畸形的自然病程及干预时机。
2
Finite element analyses, 3D-printed guides and navigation system optimizes fragment reorientation for periacetabular osteotomy.
International journal of computer assisted radiology and surgery Q3 PMID:40285833
Sheng-Hsun Lee, Sergio Guarin Perez, Adam J Wentworth, Timothy L Rossman, Rafael J Sierra
英文摘要 Abstract
Periacetabular osteotomy (PAO) is an effective treatment to correct developmental dysplasia of the hip (DDH). Traditionally, the goal of correction during PAO is based on parameters measured on 2-dimensional images. The aim of the study is to introduce an optimized workflow of PAO in DDH patients by means of personalized correction goal and accuracy of execution.
中文总结
本研究提出了一种结合有限元分析(FEA)、3D打印导板和导航系统的PAO优化工作流程。研究纳入5例DDH患者,术前通过CT进行三维规划,设定目标LCEA为25°-40°。FEA模拟单腿站立状态下不同矫正角度(±3°增量)的髋臼应力分布,以辅助术者确定最佳矫正方案。术中采用3D打印截骨导板和复位导板确保执行精度。结果显示平均手术时间101±23分钟,出血量651±176ml,LCEA从术前20.0±6.4°改善至30.2±3.1°(p=0.037),髋臼指数从12.5±3.1°降至0.8±1.6°(p=0.001)。计划矫正与实际矫正参数无显著差异(LCEA: 31.1° vs 30.2°, p=0.268),验证了执行精度。平均随访1.2年,所有截骨均愈合,疼痛评分从70分降至23分(p=0.016)。该工作流将生物力学优化与精准执行相结合,为DDH的个体化治疗提供了新思路。
3
Automated Neonatal Hip Ultrasound System for Diagnosing Developmental Dysplasia of Hips Using Assistive AI.
Journal of imaging informatics in medicine Q3 PMID:40268837
Young Seop Lee, Young Jae Kim, Jeong Won Ryu, Su Yeol Lee, Kwang Gi Kim
英文摘要 Abstract
This study aims to develop and evaluate an artificial intelligence (AI)-based diagnostic system for the diagnosis of developmental dysplasia of the hip (DDH) in infant hip ultrasonography. The Graf algorithm was employed to develop an automated model for diagnosing DDH, resulting in a DDH-assisted AI model with an average Graf angle error rate of 0.21 compared to expert diagnostics. NASNetMobile achieved the highest Area Under the Curve (AUC) of 0.864 (95% CI, 0.850-0.878), closely followed by MobileNetV1, DenseNet121, EfficientNetV2B0, NASNetMobile, and ResNet50. UnestedUNet demonstrated the highest overall performance, achieving Dice coefficients of 0.794 and a runtime of 40.078 ms, demonstrating its strong segmentation accuracy with moderate computational demands. DeepLabV3Plus, a handheld ultrasound device integrated with a smartphone, demonstrated a robust and efficient segmentation performance. This study highlights the transformative potential of integrating AI into portable ultrasound devices, enabling accurate, efficient, and accessible diagnostic solutions.
中文总结
本研究旨在开发并验证基于人工智能的婴儿髋关节超声DDH辅助诊断系统。采用Graf算法构建自动化诊断模型,AI模型与专家诊断的Graf角度平均误差率为0.21°。在分类模型中,NASNetMobile表现最优,AUC达0.864(95% CI: 0.850-0.878)。分割任务中,UnestedUNet Dice系数达0.794,运行时间仅40.078ms,在精度与效率间取得良好平衡。研究还将DeepLabV3Plus集成至手持超声设备(SONON X),实现了便携化实时分割。该系统的核心优势在于:标准化平面自动识别、Graf角度自动测量、以及可部署于便携式设备。对于临床工作而言,AI辅助诊断有望降低超声检查对操作者经验的依赖,提高DDH筛查的准确性和可及性,尤其在基层医疗机构和偏远地区具有应用价值。
4
The Relationship between Hip Ultrasound Result and the Diagnosis of Developmental Dysplasia of the Hip in Premature Infants.
American journal of perinatology Q3 PMID:40267978
Ahmed Osman, Sara Conroy, Jonathan L Slaughter
英文摘要 Abstract
The study objective was to evaluate the relationship between the first hip ultrasound (HUS) result and developmental dysplasia of the hip (DDH) diagnosis in preterm infants. Additionally, we report the types of treatment for preterm infants diagnosed with DDH.This is a retrospective chart review of infants born between January 1, 2009, and December 31, 2018, at <37 weeks of gestation who had HUS in the first year of life. Positive predictive value (PPV), negative predictive value (NPV), sensitivity, and specificity for abnormal and normal HUS results were calculated.From 2,397 infants analyzed, 71 (3%) infants were diagnosed with DDH. The majority (
中文总结
本研究为回顾性病历分析,纳入2009-2018年间2397例早产儿(<37周),评估首次髋关节超声(HUS)结果与DDH诊断的关系。结果显示DDH总体患病率3%(71/2397)。首次HUS正常者2140例(89%),其中仅5例(0.2%)后续确诊DDH。HUS的敏感性0.91、特异性0.99、阳性预测值0.8、阴性预测值0.99。196例(8%)结果不明确者中,17例(9%)后续确诊DDH。治疗方面,58%(41/71)采用Pavlik吊带保守治疗,36%(26/71)接受手术矫正。研究结论指出:正常首次HUS对排除DDH具有极高的阴性预测值(99%),异常结果阳性预测值良好(80%),而结果不明确者需密切随访。该研究为早产儿DDH筛查策略提供了循证依据,提示可根据首次超声结果进行风险分层管理。
5
Closed Reduction and Spica Cast Immobilization in Patients Aged 18 Months and Older With Developmental Dysplasia of the Hip.
Orthopaedic surgery Q3 PMID:40260515
Lei Liu, Qing-Guang Xiong, Zhen-Zhen Dai, Jing Ding, Zhen-Kai Wu
英文摘要 Abstract
For children aged 18 months and above with developmental dysplasia of the hip (DDH), treatment typically involves open reduction and hip reconstruction surgery. However, there is limited literature evaluating the efficacy of closed reduction in this patient population. The purpose of this study was to investigate the clinical efficacy of closed reduction and spica cast immobilization treatment for children aged 18 months and above with DDH, as well as the incidence of avascular necrosis of the femoral head (ANFH) and their associated risk factors.
中文总结
本研究回顾性分析2014-2020年间61例(102髋)18月龄以上DDH患儿接受闭合复位和石膏固定的疗效。采用1:1配对设计,比较闭合复位成功组与失败组。结果显示失败组IHDI分型更高(III型23.53% vs 15.69%,IV型60.78% vs 23.53%,p<0.001),术前髋臼指数更大(39.42±5.50 vs 34.03±6.15,p<0.001),术前迁移百分比更高(0.81±0.27 vs 0.54±0.36,p<0.001)。多因素分析示IHDI III-IV型是闭合复位失败的独立危险因素,较I型失败风险分别增加16.87倍和52.13倍(p<0.05)。股骨头缺血性坏死(ANFH)发生率为3.92%(4/102),均发生于闭合复位失败组。术前迁移百分比与ANFH发生相关(0.98±0.05 vs 0.66±0.34,p<0.001)。研究建议IHDI III-IV型患儿应积极考虑开放复位,以避免多次闭合复位尝试带来的ANFH风险。
6
Deep learning and conventional hip MRI for the detection of labral and cartilage abnormalities using arthroscopy as standard of reference.
European radiology Q3 PMID:40240555
Alexander W Marka, Felix Meurer, Vanessa Twardy, Markus Graf, Kilian Weiss
英文摘要 Abstract
To evaluate the performance of high-resolution deep learning-based hip MR imaging (CSAI) compared to standard-resolution compressed sense (CS) sequences using hip arthroscopy as standard of reference.
中文总结
本研究为前瞻性诊断试验,纳入32例(平均年龄37.5岁,男性24例)FAI患者,术前接受3T MRI检查,以髋关节镜为金标准,比较高分辨率深度学习重建(CSAI,0.3×0.4mm)与标准压缩感知序列(CS,0.6×0.8mm)对盂唇和软骨病变的诊断效能。三位放射科医师和一位关节镜医师独立评估。结果显示:盂唇病变检测中,两组敏感性均达97-100%(放射科)和81-90%(外科),特异性100%。软骨病变总体敏感性CSAI略优于CS(42% vs 37%,p<0.001),其中髋臼上外侧软骨敏感性最高(CS 81%,CSAI 88%,p<0.001)。但髋臼前下、后下及股骨后下、下侧区域敏感性均低于6%,提示该区域软骨评估仍是MRI的盲区。研究结论:两种序列对盂唇病变诊断效能相当,但软骨评估整体敏感性仍不理想,高分辨率深度学习重建虽略有改善,但软骨病变检测仍是术前影像的瓶颈。
7
Clinical and genetic spectrums of Mucopolysaccharidosis type IV in Duhok city, Kurdistan region, Iraq.
Cellular and molecular biology (Noisy-le-Grand, France) Q3 PMID:40235322
Azad A Haleem
英文摘要 Abstract
Mucopolysaccharidosis type IV also known as Morquio syndrome is a rare autosomal recessive lysosomal storage disorder due to deficiency of either N-acetyl-galactosamine-6-sulfatase (type A) or deficiency of beta-galactosidase (type B) which results in damages of bones, cartilages, eye corneas, skin and connective tissue. The objective of this study was to explore the relationship between specific gene mutations (c.860C>T, c.421T>A, c.1196delA) and clinical manifestations in patients with mucopolysaccharidosis type IV (MPS IV. The study was conducted at Heevi Tertiary Hospital in Duhok, Iraqi Kurdistan, till the period of September 2024, it involved 10 patients with confirmed MPS IV. Data on demographics, family history, consanguinity, skeletal, intelligence, and genetic mutations were collected. Results showed that mean age at diagnosis of 7.94 years, with females predominating. Consanguinity and family history were common. Short stature, macrocephaly, fatigue, generalized pain, and various skeletal abnormalities such as dysostosis multiplex and others. Hip dysplasia was present in 50% of patients, while intelligence was normal in most. The most frequent genetic mutation was c.860C>T, followed by c.421T>A and c.1196delA. Biochemical and hematological parameters were within normal ranges, but growth retardation was evident. Geographic clustering of mutations was noted, with c.860C>T prevalent in Zakho and c.1196delA exclusive to Akre. In conclusion, the study highlights the severe phenotypic expression associated with these mutations and underscores the influence of consanguinity and regional genetic predispositions. These findings emphasize the need for targeted genetic counseling and population screening programs in high-risk areas.
中文总结
本研究报道伊拉克杜霍克地区10例黏多糖贮积症IV型(Morquio综合征)患者的临床与遗传谱系。该罕见常染色体隐性遗传病由N-乙酰半乳糖胺-6-硫酸酯酶(IVA型)或β-半乳糖苷酶(IVB型)缺乏所致。患者平均诊断年龄7.94岁,女性多见,近亲结婚和家族史常见。主要临床表现包括身材矮小、巨头畸形、疲劳、全身疼痛及骨骼多发异常(骨发育不全等)。值得注意的是,50%(5/10)患者合并髋关节发育不良,但多数智力正常。基因突变分析示c.860C>T最常见,其次为c.421T>A和c.1196delA,且存在地域聚集性(c.860C>T多见于Zakho,c.1196delA仅见于Akre)。该研究强调了髋关节发育不良在Morquio综合征中的高发生率,对于保髋外科医师而言,在处理此类罕见病患者的髋关节病变时,需充分考虑全身骨骼系统受累的特点及潜在的基因型-表型关联。
8
Does capsulotomy in closed reduction of garden type 3 femoral neck fractures decrease incidence of avascular necrosis? A randomized controlled trial.
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie Q3 PMID:40210744
Mohamed Salama Hamdy, Ahmed O Sabry, Mahmoud Abdelazim, Rana Ali Ahmed, Ahmed Morrah
英文摘要 Abstract
Femoral neck fractures, pose significant risks of AVN and non-union. Recent studies suggest that adding capsulotomy to CRIF could reduce complications by alleviating intracapsular pressure and enhancing femoral head vascularity. This study aims to assess the efficacy of capsulotomy combined with CRIF in reducing the incidence of AVN and non-union in Garden III femoral neck fractures compared to CRIF alone.
中文总结
本研究为前瞻性随机对照试验,纳入67例18-55岁Garden III型股骨颈骨折患者,随机分为闭合复位内固定(CRIF)联合关节囊切开组(32例)和单纯CRIF组(35例),评估关节囊切开对降低股骨头坏死(AVN)和不愈合发生率的影响。结果显示关节囊切开组AVN发生率6.25%(2/32),显著低于单纯CRIF组11.4%(4/35);不愈合率0% vs 5.7%(2/35)。功能评估方面,关节囊切开组术后3个月Harris评分显著更高。研究采用随机化和盲法,增强了结果可信度。机制上,关节囊切开通过降低关节囊内压力、改善股骨头血供,从而减少AVN和不愈合风险。对于保髋外科医师而言,该研究为Garden III型股骨颈骨折的保髋治疗提供了重要证据:在闭合复位基础上加做关节囊切开,可能是一种简单有效的辅助手段,有助于改善年轻患者股骨颈骨折的预后。
9
Positive Correlation Between Acetabular Anteversion and Abduction in Developmental Dysplasia of the Hip: A CT-Based Morphological Study.
Orthopaedic surgery Q3 PMID:40204646
Tian Gao, Yuehao Hu, Yu Shan, Zhengquan Xu, Mengning Yan
英文摘要 Abstract
Developmental dysplasia of the hip (DDH) exhibits abnormalities in hip anatomy, so changes in the acetabular and femoral angles hold clinical relevance. This study aimed to investigate the correlations between acetabular anteversion (AAV) and acetabular abduction (AAB), as well as between combined anteversion and combined abduction in patients with DDH, attempting to give evidence for synchronous torsion of the proximal femur and acetabulum. This study also aimed to propose a new method for predicting acetabular anteversion and combined anteversion angles, respectively, based on acetabular abduction and combined abduction angles on conventional pelvic radiographs.
中文总结
本研究回顾性纳入202例(404髋)DDH患者,基于Crowe分型(正常93髋、I型140髋、II型68髋、III型59髋、IV型44髋),通过CT和X线片分析髋臼前倾角(AAV)与髋臼外展角(AAB)及联合前倾/外展的相关性。结果显示正常及Crowe I-III型中,联合前倾与联合外展呈显著正相关(r=0.423-0.637),AAV与AAB亦呈中度正相关(r=0.332-0.603),提示DDH患者存在髋臼与近端股骨的同步扭转现象。Crowe IV型因解剖严重变异,相关性减弱。研究进一步建立了基于X线片AAB预测AAV、联合外展预测联合前倾的线性回归方程(SH-9医院预测公式),为无CT条件下的术前规划提供了替代方案。该研究从三维形态学角度量化了DDH的同步扭转特征,对全髋关节置换的假体精准安放具有直接指导意义,也为理解DDH的病理力学机制提供了影像学依据。
10
Painful Borderline Acetabular Dysplasia: What's New?
Revista brasileira de ortopedia Q3 PMID:40177532
Rodrigo Monari, Fábio Lima Ferreira Pessiquelli, Eduardo Gomes Machado
英文摘要 Abstract
Developmental dysplasia of the hip (DDH) is a complex static-dynamic condition resulting in chronic joint instability and osteoarthritis. Borderline acetabular dysplasia refers to slightly abnormal patterns in the acetabular shape and coverage that are not within the dysplastic range. However, they can predispose to mechanical dysfunction and hip instability. Diagnosis and treatment remain controversial topics in hip preservation, with little current comparative literature to guide accurate diagnosis and treatment decision-making. Historically, the diagnosis of borderline DDH relied on assessments of the acetabular anatomy on anteroposterior pelvic radiography, most commonly the lateral central-edge angle (LCEA), with normal values ranging from 20 to 25° or, in some more recent studies, 18 to 25°. Surgical treatment decision-making debates the use of isolated hip arthroscopy or periacetabular osteotomy, considering the difficulty in determining a fundamental mechanical diagnosis (instability versus femoroacetabular impingement) in subjects with borderline DDH. Therefore, for effective surgical decision-making, the evaluation of additional bone anatomy characteristics, instability, and patients' features is essential.
中文总结
本综述系统梳理了疼痛性边缘性髋臼发育不良(borderline acetabular dysplasia)的诊断与治疗争议。边缘性DDH定义为LCEA处于临界范围(传统20-25°,近期研究扩展至18-25°),此类患者虽未达到典型发育不良标准,但存在机械功能障碍和关节不稳风险。诊断方面,单纯依赖LCEA已不足以指导临床决策,需综合评估髋臼覆盖、关节不稳及继发FAI等因素。治疗决策的核心难点在于区分不稳型与撞击型病理机制,这直接影响手术方式选择:单纯关节镜清理、关节镜联合盂唇修补、或髋臼周围截骨(PAO)。目前缺乏高质量对照研究指导个体化治疗。作者强调,术前需全面评估骨性解剖参数、关节稳定性及患者特征(年龄、活动需求),以制定精准手术方案。对于保髋外科医师,该文提示边缘性DDH的处理需要超越单一角度测量,转向多维度评估和个体化决策。
11
A deep learning algorithm for radiographic measurements of the hip versus human CT measurements: An intermodality agreement study.
Acta radiologica open Q3 PMID:40162114
Christian Greve Jensen, Benjamin Schnack Rasmussen, Søren Overgaard, Claus Varnum, Martin Haagen Haubro
英文摘要 Abstract
Hip dysplasia (HD) is a prevalent cause of non-traumatic hip pain, which may result in osteoarthritis. Radiological measurements of HD exhibit variability based on reader and imaging modality, why it is important to know the agreement between different measurement methods.
中文总结
本研究评估深度学习算法在X线片测量髋关节参数(LCEA和AIA)与CT人工测量的一致性。纳入172例患者,CT测量由放射科医师完成,X线片由AI算法自动分析。Bland-Altman分析显示:LCEA的CT与X线片平均偏差右侧5.53°(95% CI: 4.81-6.24)、左侧5.13°(95% CI: 4.43-5.83);AIA偏差右侧1.08°(95% CI: 0.49-1.67)、左侧-0.03°(95% CI: -0.60-0.05)。骨盆旋转对测量一致性有影响:闭孔指数变化0.35(LCEA)和0.6(AIA)时,测量值约变化2°。研究结论:LCEA的CT与X线片差异约5°,具有临床意义;AIA差异0-1°,临床意义有限;轻度骨盆旋转对右侧LCEA偏差影响轻微。对于保髋临床工作,该研究提示AI辅助X线测量可作为筛查工具,但LCEA的5°系统偏差需在解读时予以考虑,尤其在边界值(如20-25°)附近时,建议结合CT确认。

生成时间:2026-06-13 07:52 | 整理:小马 | 数据来源:PubMed